CYCLOSET works in a unique way
to help control blood sugar

Patient 1

Not an actual patient

CYCLOSET works in the brain to help improve how insulin works in your body

When you’re diagnosed with type 2 diabetes, your doctor will recommend a plan for you to get control of your blood sugar levels. This might include:

A healthy diet and exercise

Medication to treat and manage your diabetes

Goals for your blood sugar and A1c levels

When you’re diagnosed with type 2 diabetes, your doctor will recommend a plan for you to get control of your blood sugar levels. This might include:

A healthy diet and exercise

Medication to treat and manage your diabetes

Goals for your blood sugar and A1c levels

What is CYCLOSET?

CYCLOSET (SY-klo-set) is a once-daily prescription medicine that may help lower blood sugar levels in adults with type 2 diabetes, when used with a healthy diet and exercise. It may help you reach the goals you set with your doctor.

Your doctor may prescribe CYCLOSET as an important part of your care. To get the best possible results, your doctor may combine it with other medications.

CYCLOSET has a unique way of helping control blood sugar

CYCLOSET works in the brain to help treat insulin resistance, a main problem in type 2 diabetes. Insulin is the hormone your body produces to help change blood sugar into energy.

By unlocking your potential to use insulin more effectively, CYCLOSET helps lower your blood sugar after meals.

How does CYCLOSET work?

CYCLOSET helps boost dopamine activity in the brain. In people with type 2 diabetes, dopamine activity in the brain is believed to be too low in the morning.

More normal dopamine levels in the brain may help your body more effectively use insulin to turn glucose in the blood into energy to be used immediately or stored in the body for later use.

In clinical trials, CYCLOSET taken daily in the morning has been shown to lower blood sugar levels after each meal of the day. Over time, this may help you reach your A1c goal.

INDICATION

CYCLOSET® (bromocriptine mesylate) 0.8 mg tablets is a once-daily prescription pill used with diet and exercise to lower blood sugar levels in adults with type 2 diabetes. CYCLOSET may be taken alone or with other medicines that also help to control blood sugar. CYCLOSET has not been studied in children.

Take CYCLOSET by mouth each day within 2 hours after waking in the morning, with food. Take CYCLOSET exactly as instructed by your health care provider, and be sure to read the Patient Information section of the package insert that comes with your prescription.

IMPORTANT SAFETY INFORMATION

Do not take CYCLOSET if you:

Are allergic to bromocriptine or any of the other ingredients in CYCLOSET

Have fainting (syncopal) migraine headaches or take medicines for migraines called ergots. Ask your health care provider or pharmacist for a list of these medicines, if you are not sure whether you take any.

Are breastfeeding

Before taking CYCLOSET, tell your health care provider about all medical conditions, including if you:

Have type 1 diabetes mellitus or diabetic ketoacidosis

Have ever passed out or fainted

Have migraine headaches

Have or have had low blood pressure (hypotension)

Have or have had a mental health condition, especially a psychotic disorder

Are pregnant or plan to become pregnant. It is not known if CYCLOSET will harm your unborn baby. Talk with your health care provider if you are pregnant or plan to become pregnant.

Tell your health care provider about all medicines you take and any recent changes to your medications (prescription, non-prescription, vitamins and herbal supplements), especially those for:

Mental health conditions, especially anti-psychotic medicines

Migraine or other types of headaches

Type 2 diabetes

High blood pressure

Parkinson’s Disease

Restless leg syndrome

Endocrine related disorders such as acromegaly or hyperprolactinemia-associated dysfunctions

CYCLOSET may cause serious side effects, including:

Low blood pressure, fainting, or severe dizziness after you stand up from a lying down position

The most common side effects of CYCLOSET were:

Nausea, headache, dizziness, vomiting, and/or lightheadedness

Fatigue (somnolence) − if you have somnolence, do not drive or use other heavy equipment until the somnolence is better

Low blood sugar (hypoglycemia), especially when used with another type of diabetes medicine known as a sulfonylurea

INDICATION

CYCLOSET® (bromocriptine mesylate) 0.8 mg tablets is a once-daily prescription pill used with diet and exercise to lower blood sugar levels in adults with type 2 diabetes. CYCLOSET may be taken alone or with other medicines that also help to control blood sugar. CYCLOSET has not been studied in children.

Take CYCLOSET by mouth each day within 2 hours after waking in the morning, with food. Take CYCLOSET exactly as instructed by your health care provider, and be sure to read the Patient Information section of the package insert that comes with your prescription.

IMPORTANT SAFETY INFORMATION

Do not take CYCLOSET if you:

Are allergic to bromocriptine or any of the other ingredients in CYCLOSET

Have fainting (syncopal) migraine headaches or take medicines for migraines called ergots. Ask your health care provider or pharmacist for a list of these medicines, if you are not sure whether you take any.

Are breastfeeding

Before taking CYCLOSET, tell your health care provider about all medical conditions, including if you:

Have type 1 diabetes mellitus or diabetic ketoacidosis

Have ever passed out or fainted

Have migraine headaches

Have or have had low blood pressure (hypotension)

Have or have had a mental health condition, especially a psychotic disorder

Are pregnant or plan to become pregnant. It is not known if CYCLOSET will harm your unborn baby. Talk with your health care provider if you are pregnant or plan to become pregnant.

Tell your health care provider about all medicines you take and any recent changes to your medications (prescription, non-prescription, vitamins and herbal supplements), especially those for:

Mental health conditions, especially anti-psychotic medicines

Migraine or other types of headaches

Type 2 diabetes

High blood pressure

Parkinson’s Disease

Restless leg syndrome

Endocrine related disorders such as acromegaly or hyperprolactinemia-associated dysfunctions

CYCLOSET may cause serious side effects, including:

Low blood pressure, fainting, or severe dizziness after you stand up from a lying down position

The most common side effects of CYCLOSET were:

Nausea, headache, dizziness, vomiting, and/or lightheadedness

Fatigue (somnolence) − if you have somnolence, do not drive or use other heavy equipment until the somnolence is better

Low blood sugar (hypoglycemia), especially when used with another type of diabetes medicine known as a sulfonylurea